from Todd B. Nippoldt, M.D.Click here to view the full reply on Mayo Clinic.
If you've been diagnosed with thyroid disease, your doctor may recommend a thyroid peroxidase (TPO) antibody test — in addition to other thyroid tests — to help determine the cause. TPO, an enzyme normally found in the thyroid gland, plays an important role in the production of thyroid hormones. A thyroid peroxidase test detects antibodies against TPO in the blood.
The presence of thyroid peroxidase antibodies in your blood suggests that the cause of thyroid disease is due to an autoimmune disorder such as Hashimoto's disease or Graves' disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue. Antibodies that attack the thyroid gland cause inflammation and impaired function of the thyroid.
Your doctor may also order a thyroid peroxidase test if you are pregnant and have a thyroid disease such as Hashimoto's disease or Graves' disease. In such cases, the thyroid peroxidase te...
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