No, taking methadone and Nyquil is a bad combination and can lead to dangerous results. From personal experience, I ended up taking the two together and ended up going to bed. The next morning was my first day of school and my dad tried to wake me up. I was rushed to the hospital, I had vomited in my lungs, and was in a coma for three days with a very slim chance of living. Massive brain trauma and a disease in my lungs that almost killed me. The doctors call it a miracle that I'm still breathing today. Although I'm not sure if it will do any harm in different doses or taking at different parts of the day. Overall I think taking methadone with any kind of acoholic based liquid is dangerous.


Second Answer: I'm answering this question as well in my own experience and has nothing to do with the above. I take Methadone on a daily basis and I would suggest to not take the NyQuil close together with the Methadone. At least 4 or more hours apart. I took some la...

Disclaimer: Replies and Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on the opinions or information posted on this page. ALWAYS check with your personal physician or health care provider before taking any action regarding your health! MDinfo and our sponsors, partners, and affiliates have no obligation to monitor any replies or comments posted on this site, or the content and/or accuracy of such exchanges. MDinfo does not endorse the views of any user of this site.